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Research Critical Appraisal
Walden university

Course: NURS-6052. Essentials of Evidenced Based Practice

Research is one of the major contributors to professional development in most career fields, especially in the health care industry, since it helps healthcare providers adjust, inform, and monitor specific ways of providing care. The possibility to analyze research evidence properly is important to avoid assuming that all the carried out research are of equal quality and rationality. This paper critically analyzes some of the best practices that emerge in the research article: ‘Phillips, J. L., Jaworska, N., Kamler, E., Bhat, V., Blier, J., Foster, J. A., … & Moazamigoudarzi, Z. (2020). A randomized, crossover comparison of ketamine and electroconvulsive therapy for the treatment of major depressive episodes: a Canadian biomarker integration network in depression (CAN-BIND) study protocol. BMC Psychiatry, 20, 1-11.’ Best practices represent high-quality care, which is focused on the most favorable convincing standards of care and directs the care providers on solutions or strategies to recognize a problem.

One of the best practices that the research brings out is the high-quality patient care provision and discharge during the study. In this research, the inclusion of participants into the study followed a well provided written informed consent prior to initiating the patients into the study or any procedures related to the study. The participants chosen for the study were inpatient and outpatients who were eligible for standard ECT, and they were willing to accept allocation to either ECT or IV ketamine arms. In the research to ensure that ECT and ketamine treatment was suitable for the eligible participants, they underwent a comprehensive medical workup that involves a medical history, vital signs measurements, physical examination, pregnancy screening, and recording associated medical jurisdiction. The researchers administered ECT according to the standards of care, selecting particular treatment variables through the psychiatrist’s judgment, who was providing care. There has been established a data and safety surveilling team to check and maintain participants’ safety and treatment effectiveness in the process of the study. According to Mathew et al. (2019), this study assist individuals with major depression that is resistant to other antidepressant and the results of this research can also help the physicians to find a new treatment strategy.


Mathew, S. J., Wilkinson, S. T., Altinay, M., Asghar-Ali, A., Chang, L. C., Collins, K. A., … & Malone, D. A. (2019). ELEctroconvulsive therapy (ECT) vs. Ketamine in patients with Treatment-resistant Depression: The ELEKT-D study protocol. Contemporary Clinical Trials, 77, 19-26.

Phillips, J. L., Jaworska, N., Kamler, E., Bhat, V., Blier, J., Foster, J. A., … & Moazamigou

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